Cannabis therapy to quit smoking

 

Cannabis therapy, specifically using products containing CBD (cannabidiol) or THC (tetrahydrocannabinol), has been explored as a potential aid to quit smoking tobacco cigarettes. However, it's important to note that the research on this topic is still limited, and the effectiveness and safety of cannabis-based therapies for smoking cessation are not yet fully established.

Some studies have suggested that CBD, a non-psychoactive component of cannabis, may have potential in reducing cigarette consumption. CBD interacts with the endocannabinoid system in the body, which plays a role in regulating various physiological processes, including addiction and withdrawal. It is believed that CBD may help with smoking cessation by addressing withdrawal symptoms and cravings associated with quitting tobacco.

On the other hand, THC, the psychoactive component of cannabis, may have a more complex relationship with smoking cessation. While some research suggests that THC might reduce withdrawal symptoms, other studies indicate that THC may increase the likelihood of relapse in individuals trying to quit smoking.

It's essential to approach cannabis therapy for smoking cessation with caution, as cannabis use has its own set of potential risks and side effects, particularly when it comes to the psychoactive effects of THC. Additionally, smoking cannabis itself can still involve inhaling harmful substances into the lungs, similar to tobacco smoking.

Studies

University College London Study, 2018

The study found that after a single dose of CBD treatment, heavy daily smokers find smoking-related cues less visually attention-grabbing. As visual cues - such as seeing friends smoking - often trigger relapses in those who have quit, CBD could help people stop smoking.

For the study, 30 dependent cigarette smokers came into the lab after smoking normally or abstaining for 12 hours from smoking, and were given pills of either CBD or a placebo, on separate occasions.

The participants who received CBD showed less attentional bias to tobacco-related stimuli than in the placebo condition (to the point that their attentional bias was no greater than when satiated with nicotine when they smoked normally), and also rated smoking-related images as less pleasant.

Prior research has found that attentional bias is common in many addictive disorders, is heightened during abstinence, can predict short-term relapse, and may play a causal role in maintaining addiction.

Researchers believe that attentional bias occurs because of changes in the reward pathway of the brain caused by years of smoking, the participants' attention was drawn to drug-related images.

While craving and withdrawal symptoms were unaffected, the researchers say they will follow up with clinical trials using longer-term treatment with multiple doses, to see if craving and withdrawal symptoms will then be affected, and if CBD can help maintain abstinence.

CBD is the second most abundant cannabinoids in cannabis. Unlike tetrahydrocannabinol (THC), CBD is not intoxicating, and has been shown to have broad therapeutic benefits without harmful side effects.

Existing drugs for smoking cessation are not effective for the majority of people who take them, and some have substantial side effects. The researchers say their early results suggest that CBD is a promising candidate for a new treatment option.

Washington State University Study, 2022

The study, conducted by a team of Washington State University researchers found that CBD – the non-psychoactive component of cannabis – could inhibit the metabolism of nicotine. The researchers tested CBD on microsomes from human liver tissue and specialized cell lines to see how it influenced nicotine metabolism.

The team found that several of these enzymes, including CYP2A6 – a major one for nicotine metabolism – were inhibited, leading them to conclude that CBD could curb the urge for a cigarette.

Research suggests that more than 70% of nicotine is metabolized by this particular enzyme and that it could be inhibited by relatively low doses of CBD.

Jon Robson, CEO and founder of medical cannabis clinic Mamedica, believes CBD has the potential to be a non-addictive substitute for cigarettes and could help people quit smoking in a number of ways, including:

·         Ease stress and anxiety

CBD is often used to ease anxiety, and Robson says this can be particularly beneficial for smokers. “CBD has been shown to have anxiolytic effects, meaning that it can reduce feelings of anxiety and stress. By reducing anxiety, CBD may help people cope with the withdrawal symptoms that can occur when quitting smoking,” he says.

If smoking has been long used as a crux to manage stress and anxiety, a reduction in these feelings may see people reaching for a cigarette less and less as well.

·         Reduce nicotine cravings

“CBD may also help with craving reduction,” says Robson. “CBD has been shown to have a potential as a treatment for drug addiction, and may help reduce cravings for nicotine,” he says.

Vaporized CBD in particular may be a good alternative. As users must inhale the vapor, they are mimicking the action of smoking; a habit they might repeat several times a day. In this way, CBD could become a replacement for the repetitive motion of smoking.

·         Reduce inflammation

In addition, CBD has anti-inflammatory effects, which are beneficial to your overall health and may make quitting easier.

“Chronic smoking can lead to inflammation and damage to the lungs, which can make quitting smoking even more difficult,” Robson explains. “The anti-inflammatory properties in CBD may help to reduce inflammation and promote healing in the lungs.”

Cannabis-Based Treatment Options

Oral Consumption: Edibles and Cannabis Oil
When it comes to cannabis therapy, you have options. You can opt for oral consumption, such as edibles and cannabis oil. This method offers a discreet and long-lasting effect, perfect for those who want to kick back, relax, and bid farewell to their smoking habit.

Inhalation: Smoking and Vaporizing
If you're more of a traditionalist, you can choose the inhalation method. Smoking or vaporizing cannabis provides a more immediate effect, satisfying those who crave instant relief. Just be sure to leave the cigarettes behind as you embark on this new journey.

Topical Applications: Cannabis-infused Creams and Patches
For those who prefer not to inhale or ingest cannabis, there's still hope. Topical applications, such as cannabis-infused creams and patches, are available. These offer localized relief and can be a great option for targeting specific areas of discomfort or craving.
So, if you're ready to break free from the clutches of smoking, cannabis therapy may just be the unconventional hero you've been waiting for. Remember, though, it's always a good idea to consult a healthcare professional before starting any new treatment. Now go forth and conquer your smoke-free future with the help of some green goodness!

Best Practices for Incorporating Cannabis Therapy into Smoking Cessation

Cannabis therapy presents a promising avenue for individuals looking to quit smoking. While more research is needed to fully understand its efficacy and potential risks, the existing evidence suggests that cannabis may offer valuable benefits in reducing cravings, managing withdrawal symptoms, and improving overall well-being during the quitting process. As attitudes and regulations surrounding cannabis continue to evolve, it is important to approach its use for smoking cessation with caution and under the guidance of medical professionals. With ongoing studies and advancements in this field, the role of cannabis in combating tobacco addiction may become a significant tool in promoting a healthier and smoke-free future.